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Product Description
Retatrutide is a new weekly weight loss injection that’s still in development. Like other popular GLP-1s, it helps you feel full so you naturally eat less.
The difference is in how it works. Retatrutide has been nicknamed “Triple G” because it activates three key hormones at once: GLP-1, GIP, and GCG (glucagon). This triple effect may make it the most powerful option yet and early studies back that up.
In a phase II trial, people lost an average of 24.2% of their body weight in just 48 weeks at the highest dose. That’s more than the results seen with Wegovy (~14.9% at 68 weeks) or Mounjaro (~21% at 72 weeks).
Administration Guide
Open Retatrutide Pre-filled Pen (30 mg) Administration Guide (PDF)
Dosing Information (Based on Clinical Trials)
Retatrutide does not yet have an official approved dosing schedule, as it is still in development. However, phase II studies have used the following titration approach:
Example escalation from trials:
1-4 weeks → 1 mg
5-8 weeks → 2 mg
9-12 weeks → 4 mg
13-16 weeks → 8 mg
17+ weeks → up to 12 mg (if tolerated)
Notes:
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